Novel Extracorporeal Magnetotransduction Therapy with Magnetolith® and Focused Electromagnetic Extracorporeal Shockwave Therapy in Medial Meniscal Tear – A Case Report

Case Report | Volume 2 | Issue 1 | JRS Jan – Jun 2022 | Page 32-35 | Karsten Knobloch

DOI: 10.13107/jrs.2022.v02.i01.43

Author: Karsten Knobloch [1]

[1] Sport Praxis Prof. Knobloch, Hannover, Germany.

Address of Correspondence
Prof. Dr. Karsten Knobloch,
Heiligerstr. 3, Hannover – 30159, Germany.


The case report describes a non-invasive combination of novel extracorporeal magnetotransduction therapy (EMTT) with focused extracorporeal shockwave therapy for symptomatic medial meniscal tear in a 41-year-old gentleman. Ultra-high-frequency 33 MHz ultrasound revealed a complex medial meniscal tear with a ganglion confirmed by subsequent magnetic resonance imaging. Non-invasive treatment with combined novel Magnetolith® EMTT with focused electromagnetic extracorporeal shockwave therapy for three sessions on a weekly interval. Shear wave elastography at 6 months demonstrated comparable stiffness of the healed and the healthy contralateral meniscus. The healing of the meniscal tear could be depicted by multiparametric ultra-high-frequency ultrasound (33 MHz) with novel stress testing and shear wave elastography.

Keywords: Magnetic field, Extracorporeal shockwave therapy, Extracorporeal shockwave therapy, Meniscal, Ultrasound, Pain


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How to Cite this article: Knobloch K | Novel Extracorporeal Magnetotransduction Therapy with Magnetolith® and Focused Electromagnetic Extracorporeal Shockwave Therapy in Medial Meniscal Tear – A Case Report | Journal of Regenerative Science | Jan – Jun 2022; 2(1): 32-35.

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Extracorporeal Shockwave Treatment for Managing Biofilm-mediated Infections in Dentistry: Current Knowledge and Future Perspectives

Review Article | Volume 2 | Issue 1 | JRS Jan – Jun 2022 | Page 22-26 | Antonia Olivares, Christina M A P Schuh, Sebastian Aguayo

DOI: 10.13107/jrs.2022.v02.i01.39

Author: Antonia Olivares [1], Christina M A P Schuh [2], Sebastian Aguayo [1,3]

[1] School of Dentistry, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.

[2] Centro de Medicina Regenerativa, Facultad de Medicina, Clínica Alemana-Universidad del Desarrollo, Santiago, Chile.

[3] Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.

Address of Correspondence
Dr. Sebastian Aguayo,
School of Dentistry and Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.


At present, chronic non-communicable diseases are becoming more prevalent across the world. Among these pathologies, oral diseases such as dental caries and periodontitis are some of the most frequently observed in populations worldwide. These biofilm-mediated infections are produced as a consequence of a series of factors that modify the oral microenvironment and lead to dysbiosis among residing biofilms, which are particularly difficult to treat with pharmacological approaches due to their structural and anatomical characteristics. Furthermore, the recent sharp increase in antimicrobial resistance has potentiated the need for the development of novel techniques to effectively treat biofilm-mediated diseases in the mouth. One option that has recently shown promising results in vitro is the use of focused high-energy extracorporeal shockwave therapy (fhESWT) for the control of microbial growth and biofilm formation. Several studies have shown the effect of fhESWT on the treatment of biofilm-mediated infections associated with bone fractures and orthopedic implant infection, although the mechanisms behind this effect are still unknown. Regarding the oral cavity, there remains a lack of clinical studies but there are some limited in vitro and in vivo investigations that shed light on the potential of fhESWT for biofilm control. Therefore, the objective of this review is to discuss the most relevant available literature regarding the in vitro and in vivo effects of fhESWT over biofilm control, as well as the potential use of fhESWT for the treatment of oral biofilm-mediated diseases in the future.

Keywords: Bacteria, Biofilms, Extracorporeal shockwave therapy, Focused high-energy extracorporeal shockwave therapy, Fungi, Microorganisms.


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How to Cite this article: Olivares A, Schuh CMAP, Aguayo S | Extracorporeal Shockwave Treatment for Managing Biofilm-mediated Infections in Dentistry: The Current Knowledge and Future Perspectives | Journal of Regenerative Science | Jan – Jun 2022; 2(1): 22-26.

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Very Low and Low-energetic Extracorporeal Shock Wave Treatment of Spasticity in Children and Adults – A Systematic Review

Systematic Review | Volume 2 | Issue 1 | JRS Jan – Jun 2022 | Page 03-08 | Karsten Knobloch, Henning Lohse-Busch, Andreas Gohritz, Tomas Nedelka

DOI: 10.13107/jrs.2022.v02.i01.33

Author: Karsten Knobloch [1], Henning Lohse-Busch [2], Andreas Gohritz [3], Tomas Nedelk [4,5]

[1] Department of Sports Medicine, SportPraxis Prof. Knobloch, Hannover, Germany.

[2] Zentrum für Bewegungsstörungen, Rheintalklinik Bad Krozingen, Germany.

[3] Department of Neurology, Universitätsspital Basel, Plastische, Rekonstruktive und Ästhetische Chirurgie, Handchirurgie, Suisse.

[4] Department of Neurology, Charles University in Prague, 2nd Faculty of Medicine, Prague, Czech Republic.

[5] Department of Neurology, Czech Technical University, Faculty of Biomedical Engineering, Kladno, Czech Republic.

Address of Correspondence
Prof. Dr. Karsten Knobloch,
SportPraxis Prof. Knobloch, Heiligerstr. 3, D-30159 Hannover, Germany.


Introduction: This systemic review aims to assess the modes and treatment parameters of radial and focused extracorporeal shockwave therapy (ESWT) in spasticity based on the technologies and energy levels involved.
Materials and Methods: 1086 patients from 31 randomized-controlled trials (RCT) or cohort studies are included. 300 children were studied in seven studies (3 RCTs) with two radial and four focused electromagnetic ESWT devices and 14 studies with 443 patients using focused ESWT (electrohydraulic 46 patients, electromagnetic 367 patients, and piezoelectric 30 patients).
Results: In electromagnetic focused ESWT 8 RCTs (n = 323 patients) and three cohort studies (n = 44) used either very low-energetic (0.03–0.05 mJ/mm2) with 1500–2000 shots and 4–5 Hz with 3–5 focused sessions, or low-energetic 0.07–0.12 mJ/mm2 with 1500–2000 shots with 4–5 Hz and 1–3 sessions. The 64 children in the five electromagnetic focused trials were treated with very low-energetic 0.03 mJ/mm2, 1500 shots, and three sessions. 17 studies (n = 687) were using radial technologies with 7 RCTs (n = 349) and ten cohort studies (n = 338). Among the 17 trials, four studies (1 RCT, 3 cohort studies) included 236 children treated with either very low-energetic 0.6–1 bar (two trials) or low-energetic 1.5–3 bar with 5–10 Hz. Energy-wise three radial studies were very low-energetic 0.6–1 bar and 14 studies applied low-energetic radial pressures 1.5–3 bar. Notably, the frequency was mainly 4–8 Hz in the radial studies.
Conclusion: Both, radial and focused very low- to low-energetic ESWT improve function and reduce spasticity significantly. Adverse effects were not noted with the applied very low- to low-energetic device parameters neither among children nor in adults.

Keywords: Spasticity, Extracorporeal shock wave therapy, Extracorporeal shockwave therapy, Children.


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How to Cite this article: Knobloch K, Lohse-Busch H, Gohritz A, Nedelka T | Very Low and Low-energetic Extracorporeal Shock Wave Treatment of Spasticity in Children and Adults–A Systematic Review. | Journal of Regenerative Science | Jan – Jun 2022; 2(1): 03-08.

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