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The History of Shock Wave Medicine Development in China

December 30, 2023/0 Comments/in Vol 3 | Issue 2 | Jul-Dec 2023/by Editor JRS

Editorial | Vol 3 | Issue 2 | July-December 2023 | page: 03-04 | Shuitao Liu, Gengyan Xing DOI: https://doi.org/10.13107/jrs.2023.v03.i02.87 Author: Shuitao Liu [1], Gengyan Xing [2] [1] Department of Traumatic Orthopedics, Armed Police Characteristic Medical Center., Tianjin, China, [2] Corresponding author: Gengyan Xing, Department of Orthopedic, The Third Medical Center of Chinese People’s Liberation […]

Shock Wave Medicine: A Transformative Evolution in Modern Medicine

December 30, 2023/0 Comments/in Vol 3 | Issue 2 | Jul-Dec 2023/by Editor JRS

Original Article | Vol 3 | Issue 2 | July-December 2023 | page: 05-09 | Sunte Li, Xiaoyu Fan, Wei Sun DOI: https://doi.org/10.13107/jrs.2023.v03.i02.89 Author: Sunte Li [1], Xiaoyu Fan [2], Wei Sun [3, 4] [1] Friends Central School, Philadelphia, Pennsylvania, USA, [2] Department of Surgery, Peking University People’s Hospital, Beijing, China, [3] Department of Orthopaedic […]

The History of Shock Wave Medicine Development in China

December 30, 2023/0 Comments/in Vol 3 | Issue 2 | Jul-Dec 2023/by Editor JRS

Shock Wave Medicine: A Transformative Evolution in Modern Medicine

December 30, 2023/0 Comments/in Vol 3 | Issue 2 | Jul-Dec 2023/by Editor JRS

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The History of Shock Wave Medicine Development in China

December 30, 2023/0 Comments/in Vol 3 | Issue 2 | Jul-Dec 2023/by Editor JRS

DOI: https://doi.org/10.13107/jrs.2023.v03.i02.87

Author: Shuitao Liu [1], Gengyan Xing [2]

[1] Department of Traumatic Orthopedics, Armed Police Characteristic Medical Center., Tianjin, China,
[2] Corresponding author: Gengyan Xing, Department of Orthopedic, The Third Medical Center of Chinese People’s Liberation Army General Hospital, Beijing, China.

Address of Correspondence
Dr. Gengyan Xing,
Department of Orthopedic, The Third Medical Center of Chinese People’s Liberation Army General Hospital, Beijing,
China.
E-mail: xgy1350138@163.com

Editorial

The development of shock wave medicine in China can be traced back to the 1980s. At that time, shock waves were applied to treat urinary tract stones with good results. In 1993, Professor Xing Gengyan pioneered the application of extracorporeal shock wave therapy for humeral epicondylitis, marking a significant milestone in the advancement of shock wave medicine in China. With the deepening of research on shock waves and technological advancements, the indications for shock wave medicine have been continuously expanded, achieving good results in treating bone tissue diseases such as delayed fracture healing and non-union. To further promote the experience of shock wave therapy, Professor Xing Gengyan successively held 8 national continuing education programs on “Extracorporeal Shock Wave Therapy for Bone and Muscle Disorders,” training thousands of doctors who mastered shock wave therapy techniques. With the conduct of numerous clinical studies and accumulation of data, the China National Medical Products Administration approved the domestic production of extracorporeal shock wave therapy machines for treating orthopedic diseases in August 2000, marking the official entry of shock wave medicine into a high-speed development phase in China.
As clinical applications continue to advance and expand, Chinese scholars have begun to explore the mechanisms of action of shock waves. In 2004, Professor Xing Ganyan’s research on “Osteoblast Mechanochemical Signal Transduction and Related Gene Expression Following ESWT” was funded by the National Natural Science Foundation of China, resulting in a wealth of published findings. In 2007, Professor Xing Ganyan edited and published the first monograph on shock wave medicine, <Extracorporeal Shock Wave Therapy for Bone and Muscle Diseases (First Edition)>, which consists of two parts and eight chapters. This comprehensive summary of over a decade of clinical application experience and foundational research laid the foundation for shock wave medicine in China.
With the rapid advancement of China’s medical level, Chinese scholars’ research on shock waves has gradually gained global recognition. A significant number of papers on shock waves published by Chinese scholars has been indexed, and their research achievements have been communicated at international conferences. Concurrently, as the depth of research on shock wave therapy increases and instruments advance, shock waves are no longer confined to treating urinary tract stones, non-unions, osteonecrosis, and tendinopathy [1-4]. They have also achieved promising results in treating myocardial infarction, skin ulcers, tumors, nerve injuries, and male dysfunction, among others.
In December 2013, the Chinese Shock Wave Medicine Professional Committee was established in Beijing, with Professor Xing Gengyan serving as the inaugural Chairman. Since then, shock wave medicine has had an independent academic organization. Building on past experiences, in 2014, the <Expert Consensus on Extracorporeal Shock Wave Therapy for Bone and Muscle Diseases> was released [5], significantly advancing the scientific and standardized development of shock wave medicine. In 2015, the <Extracorporeal Shock Wave Therapy for Bone and Muscle Diseases (Second Edition)> was published, expanding the volume to 5 articles and 19 chapters, with a significant addition of numerous recent research findings. In July 2016, at the annual meeting of the international society for medical shock wave treatment (ISMST) held in Malaysia, Professor Xing Gengyan was elected as the President of the ISMST. China secured the hosting rights for the 22nd annual conference in 2019, signifying that China is at the forefront of shock wave medicine development worldwide.
The year 2019 marked the most memorable year in the history of shock wave development in Chinese medicine. Building upon the previous two editions of the <Expert Consensus on Extracorporeal Shock Wave Therapy for Bone and Muscle Diseases>, Chinese scholars integrated evidence-based medical experiences and released the <Chinese Guidelines for Extracorporeal Shock Wave Therapy for Bone and Muscle Diseases (2019 Edition) [6], thereby standardizing and scientifically advancing the application of shock waves in China. In May of the same year, the ISMST 22nd International Congress on Medical Shock Waves convened in Beijing, attended by over 1,200 experts and scholars from nearly 30 countries. This was the largest-attended conference in the history of shock wave medicine, covering the broadest range of academic interests and delving into the most in-depth discussions on various research topics, significantly advancing the development of shock wave medicine in China.
Currently, over 3,000 hospitals in China possess extracorporeal shock wave therapy systems, covering treatment fields such as orthopedics, urology, plastic surgery, cardiology, stomatology, oncology, and rehabilitation, treating millions of patients annually [7-9]. Concurrently, Chinese scholars in the field of shock wave therapy are continually innovating, integrating extracorporeal shock waves with techniques such as arthroscopy, stem cells, and nanomaterials to achieve synergistic therapeutic effects, resulting in favorable outcomes [10-12]. Each year, over 500 related research papers are published.
Further, elucidating the biological mechanisms of shock waves in clinical efficacy at the organizational, cellular, and molecular levels will continuously expand the application scope of shock waves. In response to the relative lack of high-level evidence for shock wave research, the China Shock Wave Medical Association is organizing multi-center, large-sample clinical studies; standardized training for practitioners and accreditation of treatment institutions have also been put on the agenda. It is believed that in the near future, China’s shock wave medicine will witness a richer array of research achievements, bringing blessings to more patients.

References:

1. Xing G. The past, present and future of shockwave medicine. Chin J Front Med Sci 2014;6:1-2.
2. Wang Y, Guo T, Cai HY, Ma TK, Tao SM, Sun S, et al. Cardiac shock wave therapy reduces angina and improves myocardial function in patients with refractory coronary artery disease. Clin Cardiol 2010;33:693-9.
3. Liu J, Zhou F, Li GY, Wang L, Li HX, Bai GY, et al. Evaluation of the effect of different doses of low energy shock wave therapy on the erectile function of streptozotocin (STZ)-induced diabetic rats. Int J Mol Sci 2013;14:10661-73.
4. Yan X, Yang G, Cheng L, Chen M, Cheng X, Chai Y, et al. Effect of extracorporeal shock wave therapy on diabetic chronic wound healing and its histological features. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2012;26:961-7.
5. Xing G, Huang C, Huang Z, Li Y, Li Z, Liu Y, et al. Professional Committee of Shock Wave Medicine of Chinese Research Hospital Association. Expert consensus of extracorporeal shock wave therapy for bone and muscle diseases. Chin J Front Med Sci 2014;6:170-7.
6. Xing G, Zhang H, Liu S, Zhao Z. Chinese guidelines for extracorporeal shockwave therapy for bone and muscle diseases (2019 Edition). Chin J Front Med Sci 2019;11:1-10.
7. Xu Y, Wu K, Liu Y, Geng H, Zhang H, Liu S, et al. The effect of extracorporeal shock wave therapy on the treatment of moderate to severe knee osteoarthritis and cartilage lesion. Medicine (Baltimore) 2019;98:e15523.
8. Li F, Zhen Z, Sun SJ, Jiang Y, Liang WH, Belau M, et al. Attenuation of myocardial dysfunction in hypertensive cardiomyopathy using non-R-wave-synchronized cardiac shock wave therapy. Int J Mol Sci 2022;23:13274.
9. Huang Q, Yan P, Xiong H, Shuai T, Liu J, Zhu L, et al. Extracorporeal shock wave therapy for treating foot ulcers in adults with type 1 and type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials. Can J Diabetes 2020;44:196-204.e3.
10. Liang H, Chen K, Xie J, Yao L, Liu Y, Hu F, et al. A bone-penetrating precise controllable drug release system enables localized treatment of osteoporotic fracture prevention via modulating osteoblast-osteoclast communication. Small 2023;19:e2207195.
11. Bai X, Gao Y, Zhang M, Chang YN, Chen K, Li J, et al. Carboxylated gold nanoparticles inhibit bone erosion by disturbing the acidification of an osteoclast absorption microenvironment. Nanoscale 2020;12:3871-8.
12. Zeng L, Geng H, Gu W, Ma S, Qin Y, Xia S, et al. Au nanoparticles attenuate RANKL-induced osteoclastogenesis by suppressing pre-osteoclast fusion. J Nanosci Nanotechnol 2019;19:2166-73.

How to Cite this article: Liu S, Xing G | The History of Shock Wave Medicine Development in China. | Journal of Regenerative Science | Jul-Dec 2023; 3(2): 03-04.

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Shock Wave Medicine: A Transformative Evolution in Modern Medicine

December 30, 2023/0 Comments/in Vol 3 | Issue 2 | Jul-Dec 2023/by Editor JRS

DOI: https://doi.org/10.13107/jrs.2023.v03.i02.89

Author: Sunte Li [1], Xiaoyu Fan [2], Wei Sun [3, 4]

[1] Friends Central School, Philadelphia, Pennsylvania, USA,
[2] Department of Surgery, Peking University People’s Hospital, Beijing, China,
[3] Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA,
[4] Department of Orthopedics, Shockwave Center, China-Japan Friendship Hospital, Chaoyang, Beijing, China.

Address of Correspondence
Dr. Wei Sun,
Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA/Department of Orthopedics, Shockwave Center, China-Japan Friendship Hospital, Chaoyang, Beijing, China.
E-mail: wei.sun@pennmedicine.upenn.edu

Abstract

Since its inception as extracorporeal shock wave lithotripsy in the 1980s, the landscape of medical treatment has been revolutionized by the evolution of shock wave therapy. Over four decades, this therapy, now known as extracorporeal shock wave therapy (ESWT), has emerged as a cornerstone in modern medicine, redefining treatment paradigms across various medical disciplines. Certainly, despite the promising outcomes witnessed in various medical conditions such as musculoskeletal disorders, wound healing, urinary calculi, and erectile dysfunction,
it is crucial to acknowledge that shock wave therapy’s relatively short clinical tenure necessitates a cautious approach. While its effectiveness has been repeatedly demonstrated, establishing industry-standard protocols through large-scale, prospective randomized controlled trials remains imperative to solidify its standing in medical practice.
The integration of Artificial Intelligence technology holds significant promise for the future of shockwave medicine, enabling personalized treatment plans, real-time feedback, and improved cost-effectiveness.
Keywords: Shock waves, ESWT, Shockwave

References:

1. Seoane LM, Salvador JB, Alba A, Fentes DA. Technological innovations in shock wave lithotripsy. Actas Urol Esp (Engl Ed) 2024; (48)-1:105-110. https://doi.org/10.1016/j.acuroe.2023.09.001
2. Moya D, Ramón S, Schaden W, Wang CJ, Guiloff L, Cheng JH. The role of extracorporeal shockwave treatment in musculoskeletal disorders. J Bone Joint Surg Am 2018;100:251-63.
3. Porst H. Review of the current status of low intensity extracorporeal shockwave therapy (Li-ESWT) in erectile dysfunction (ED), Peyronie’s disease (PD), and sexual rehabilitation after radical prostatectomy with special focus on technical aspects of the different marketed ESWT devices including personal experiences in 350 patients. Sex Med Rev 2021;9:93-122.
4. Van der Worp H, Van den Akker-Scheek I, Van Schie H, Zwerver J. ESWT for tendinopathy: Technology and clinical implications. Knee Surg Sports Traumatol Arthrosc 2013;21:1451-8.
5. Schroeder AN, Tenforde AS, Jelsing EJ. Extracorporeal shockwave therapy in the management of sports medicine injuries. Curr Sports Med Rep 2021;20:298-305.
6. Wang H, Shi Y. Extracorporeal shock wave treatment for post-surgical fracture nonunion: Insight into its mechanism, efficacy, safety and prognostic factors (Review). Exp Ther Med 2023;26:332.
7. Simplicio CL, Purita J, Murrell W, Santos GS, Dos Santos RG, Lana JF. Extracorporeal shock wave therapy mechanisms in musculoskeletal regenerative medicine. J Clin Orthop Trauma 2020;11:S309-18.
8. Wigley CH, Janssen TJ, Mosahebi A. Shock wave therapy in plastic surgery: A review of the current indications. Aesthet Surg J 2023;43:370-86.
9. Kuo YR, Wang CT, Wang FS, Chiang YC, Wang CJ. Extracorporeal shock-wave therapy enhanced wound healing via increasing topical blood perfusion and tissue regeneration in a rat model of STZ-induced diabetes. Wound Repair Regen 2009;17:522-30.
10. Lee SY, Joo SY, Cho YS, Hur GY, Seo CH. Effect of extracorporeal shock wave therapy for burn scar regeneration: A prospective, randomized, double-blinded study. Burns 2021;47:821-7.
11. Yao H, Wang X, Liu H, Sun F, Tang G, Bao X et al. Systematic Review and Meta-Analysis of 16 Randomized Controlled Trials of Clinical Outcomes of Low-Intensity Extracorporeal Shock Wave Therapy in Treating Erectile Dysfunction. Am J Mens Health. 2022 Mar-Apr;16(2):15579883221087532. doi: 10.1177/15579883221087532. PMID: 35319291; PMCID: PMC8949743.
12. Dong L, Chang D, Zhang X, Li J, Yang F, Tan K, et al. Effect of low-intensity extracorporeal shock wave on the treatment of erectile dysfunction: A systematic review and meta-analysis. Am J Mens Health 2019;13:2. Published online. Open access: https://journals.sagepub.com/action/showCitFormats?doi=10.1177%2F1557988319846749&mobileUi=0
13. Wu WL, Bamodu OA, Wang YH, Hu SW, Tzou KY, Yeh CT, et al. Extracorporeal shockwave therapy (ESWT) alleviates pain, enhances erectile function and improves quality of Life in patients with chronic prostatitis/chronic pelvic pain syndrome. J Clin Med 2021;3602.
14. Radu CA, Kiefer J, Horn D, Rebel M, Koellensperger E, Gebhard MM, et al. Shock wave treatment in composite tissue allotransplantation. Eplasty 2011;11:e37.
15. Li HX, Zhang ZC, Peng J. Low-intensity extracorporeal shock wave therapy promotes recovery of sciatic nerve injury and the role of mechanical sensitive YAP/TAZ signaling pathway for nerve regeneration. Chin Med J (Engl) 2021;134:2710-20.
16. Mittermayr R, Hartinger J, Antonic V, Meinl A, Pfeifer S, Stojadinovic A, et al. Extracorporeal shock wave therapy (ESWT) minimizes ischemic tissue necrosis irrespective of application time and promotes tissue revascularization by stimulating angiogenesis. Ann Surg 2011;253:1024-32.
17. Yamaya S, Ozawa H, Kanno H, Kishimoto KN, Sekiguchi A, Tateda S, et al. Low-energy extracorporeal shock wave therapy promotes vascular endothelial growth factor expression and improves locomotor recovery after spinal cord injury. J Neurosurg 2014;121:1514-25.
18. López-Marín LM, Rivera AL, Fernández F, Loske AM. Shock wave-induced permeabilization of mammalian cells. Phys Life Rev 2018;26-27:1-38.
19. Yeh KH, Sheu JJ, Lin YC, Sun CK, Chang LT, Kao YH, et al. Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats. Crit Care Med 2012;40:169-77.
20. Reichenberger MA, Heimer S, Schaefer A, Lass U, Gebhard MM, Germann G, et al. Extracorporeal shock wave treatment protects skin flaps against ischemia-reperfusion injury. Injury 2012;43:374-80.
21. Sung PH, Fu M, Chiang HJ, Huang CR, Chu CH, Lee MS, et al. Reduced effects of cardiac extracorporeal shock wave therapy on angiogenesis and myocardial function recovery in patients with end-stage coronary artery and renal diseases. Biomed J 2021;44:S201-9.
22. Oktaş B, Orhan Z, Erbil B, Değirmenci E, Ustündağ N. Effect of extracorporeal shock wave therapy on fracture healing in rat femural fractures with intact and excised periosteum. Eklem Hastalik Cerrahisi 2014;25:158-62.
23. Qiao HY, Xin L, Wu SL. Analgesic effect of extracorporeal shock-wave therapy for frozen shoulder: A randomized controlled trial protocol. Medicine (Baltimore) 2020;99:e21399.
24. Fiani B, Davati C, Griepp DW, Lee J, Pennington E, Moawad CM. Enhanced spinal therapy: Extracorporeal shock wave therapy for the spine. Cureus 2020;12:e11200.
25. Özkan E, Şenel E, Bereket MC, Önger ME. The effect of shock waves on mineralization and regeneration of distraction zone in osteoporotic rabbits. Ann Med 2023;55:1346-54.
26. Shi L, Gao F, Sun W, Wang B, Guo W, Cheng L, et al. Short-term effects of extracorporeal shock wave therapy on bone mineral density in postmenopausal osteoporotic patients. Osteoporos Int 2017;28:2945-53.
27. Hao L, Liu Y, Wang T, Guo HL, Wang D, Bi YW, et al. Extracorporeal shock wave lithotripsy is safe and effective for geriatric patients with chronic pancreatitis. J Gastroenterol Hepatol 2019;34:466-73.
28. Klang E, Portugez S, Gross R, Lerner KR, Brenner A, Gilboa M, et al. Advantages and pitfalls in utilizing artificial intelligence for crafting medical examinations: A medical education pilot study with GPT-4. BMC Med Educ 2023;23:772.
29. Wójcik S, Rulkiewicz A, Pruszczyk P, Lisik W, Poboży M, Domienik-Karłowicz J. Beyond ChatGPT: What does GPT-4 add to healthcare? The dawn of a new era. Cardiol J 2023;30:1018-25.
30. Mun C, Ha H, Lee O, Cheon M. Enhancing AI-CDSS with U-AnoGAN: Tackling data imbalance. Comput Methods Programs Biomed 2023;244:107954.
31. Palavicini G. Intelligent health: Progress and benefit of artificial intelligence in sensing-based monitoring and disease diagnosis. Sensors (Basel) 2023;23:9053.

How to Cite this article: Li S, Fan X, Sun W. | Shock Wave Medicine: A Transformative Evolution in Modern Medicine. | Journal of Regenerative Science | Jul-Dec 2023; 3(2): 05-09.

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The History of Shock Wave Medicine Development in China

Shock Wave Medicine: A Transformative Evolution in Modern Medicine

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