Original Article | Vol 5 | Issue 2 | July-December 2025 | page: 20-27 | Na Chen
DOI: https://doi.org/10.13107/jrs.2025.v05.i02.175
Open Access License: CC BY-NC 4.0
Copyright Statement: Copyright © 2025; The Author(s).
Submitted Date: 25 Oct 2025, Review Date: 12 Nov 2025, Accepted Date: Nov 2025 & Published: 30 Dec 2025
Author: Na Chen [1]
[1] Department of Internal Medicine, Peking University Hospital, Beijing, China
Address of Correspondence
Na Chen,
Department of Internal Medicine, Peking University Hospital, Beijing, China. E-mail: 18901267905@163.com; CN09558@pku.edu.cn.
Abstract
Purpose: Extracorporeal shock wave therapy (ESWT) has emerged as a promising non-invasive intervention in cardiovascular disease (CVD) management, with increasing research interest over the past two decades. This study aimed to systematically analyze the research progress, hotspots, and development trends in ESWT for CVD using bibliometric methods, providing a comprehensive overview for subsequent research.
Methods: Literature related to ESWT and CVD was retrieved from the Web of Science Core Collection database, covering the period from 1999 to August 2025. The search strategy was defined as TS=([Shock wave OR Extracorporeal shock wave therapy OR ESWT] AND [Cardiovascular disease OR Coronary artery disease OR Myocardial ischemia OR Heart failure]). After excluding non-English studies, proceeding papers, retracted publications, and early access articles, 465 valid articles were included. Bibliometric analysis was performed using VOSviewer and CiteSpace software, focusing on publication trends, country/institution contributions, author collaborations, journal distributions, keyword co-occurrence, and cited references.
Results: A total of 465 publications involving 3019 authors from 1001 institutions across 55 countries were included, with 15,556 citations from 3104 sources. The annual number of publications has shown a steady growth trend since 2017. The United States (133 documents, 53.3 average citations) was the most influential country, followed by China (82 documents) and Germany (47 documents). Tohoku University (20 documents, 56.1 average citations) and Mayo Clinic (11 documents, 79.7 average citations) were leading institutions. Hiroaki Shimokawa and Hon-Kan Yip (18 documents each) were the most productive authors. Heart Rhythm (15 documents, 44.8 average citations) and Circulation (9 documents, 140.2 average citations) were core journals in this field. High-frequency keywords included “heart failure” (56 times), “coronary artery disease” (44 times), and “mortality” (41 times), with “outcome” being recent burst terms (2023–2025). The top-cited reference was a 2004 study on ESWT improving ischemia-induced myocardial dysfunction in pigs (87 citations).
Conclusion: ESWT for CVD is a rapidly developing research field, with the United States leading in academic influence. Current research focuses on myocardial ischemia, heart failure, and therapeutic efficacy/safety, while future trends may involve exploring mechanisms related to extracorporeal shock wave action and expanding clinical applications in comorbidities.
Keywords: Extracorporeal shock wave therapy, Cardiovascular disease, Bibliometrics, CiteSpace, VOSviewer
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How to Cite this article: Chen N . Visual analysis of research progress and trends in extracorporeal shock wave therapy for coronary heart disease. Journal of Regenerative Science. July-Decemnber 2025;5(2):20-27
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